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Larry Sandler was a "leading ''Drosophila'' geneticist",〔Dan Lindsley, ("Larry Sandler: Personal Recollections" ), ''Genetics'' 151: 1233–1237 (April 1999)〕 active during the mid-20th century, and best known for his work on meiotic drive. Sandler earned a B.S. at Cornell University, and did his doctoral work with Ed Novitski at the University of Missouri, where he collaborated with Gerry Braver.〔Dan Lindsley, ("Larry Sandler: The Father of Meiotic Drive" ), ''The American Naturalist'', Vol. 137, No. 3, pp.283-286 (March 1991).〕 Braver and Sandler discovered that meiotic chromosomal loss was one driver of allelic variation in natural populations,〔 (Sandler & Braver 1954.〔Sandler & Braver 1954〕) a phenomenon coined "meiotic drive" in a follow-up paper by Sandler and Novitski.〔 (Sandler & Novitski 1957.〔Sandler & Novitski 1957〕) Sandler also collaborated with Iris Sandler, his wife and fellow scientist, who also worked as a graduate student in Novitski's lab.〔 In 1956, Sandler briefly joined the Biology Division at Oak Ridge National Laboratory, where Sandler and Dan Lindsley worked on sperm dysfunction.〔 After joining the lab of Jim Crow at the University of Wisconsin, Sandler and Yuichiro Hiraizumi began working on segregation distortion, publishing several papers together.〔B. Ganetzky, "Yuichiro Hiraizumi and forty years of segregation distortion", ''Genetics'' (1999).〕 Sandler moved to the University of Washington in 1962.〔 There he supervised numerous graduate students who joined the field, including Bruce Baker, Adelaide T. Carpenter, Ian Duncan, Barry Ganetzky, Larry Goldstein, Kent Golic, Jeff Hall, Scott Hawley, Jim Mason, John Merriam, Joe O'Tousa, Leonard Robbins, Paul Szauter, Bill Sullivan, Jon Tomkiel, and Glenn Yasuda.〔 Sandler was professionally active, involved in the founding of the Drosophila Research Conference, and transferring it to the Genetics Society of America.〔 He was also involved with other conferences, including the International Congress of Genetics, and as editor with numerous genetics journals, including ''Annual Review of Genetics'' and ''Genetics''.〔 Sandler was married to fellow scientist Iris Sandler, who ultimately became a historian of science.〔 The couple had two children, Jack and Dee Sandler.〔 He died in 1987.〔 ==Significant papers== * Sandler & Braver 1954, "The meiotic behavior of grossly deleted X chromosomes in ''Drosophila melanogaster''", ''Genetics'' v.43, pp. 547–563. * Sandler & Novitski 1957, "Meiotic drive as an evolutionary force," ''American Naturalist'' v.91, pp. 105–110. * D. L. Lindsley & L. Sandler, 1958, "The meiotic behavior of grossly deleted X chromosomes in ''Drosophila melanogaster''", ''Genetics'', 43:547-563. * Larry Sandler and Yuichiro Hiraizumi, 1960, "Meiotic drive in natural populations of ''Drosophila melanogaster''", ''Genetics'', 45:1671-1689 ("On the nature of the ''SD'' region"). 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Larry Sandler」の詳細全文を読む スポンサード リンク
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